Letters From Generation RX | Journeyman Pictures (2024)

Letters from Generation Rx

afilm by Kevin P. Miller

©2017 KolaFilms LLC

Letters from Generation RXComplete

Opens withhaunting music as shots of Rocky Mountains are revealed;

Autumn: Ive had to renegotiate that memory over and over andover again.

(old Churchin the middle of nowhere as musical chant begins)

Autumn: gravel spitting and water flying and kids screaming

(photo ofAutumn as youngster)

Autumn: It was the summer after I turnedeight

(long shotreveals rural road as 1990 Ford Bronco appears)

Autumn: We never really knew what toyexpect from Mom. During a particularly bad swing, she went through some reallydesperate days .. and she put us all in the Bronco and took us for a drive downto the river.

(soulfulchant continues as low angle of Bronco speeds by)

Autumn: Before we got to the river, shewas just purely robotic. She decided it was time for all of us .. to die. Its time to die; were all gonna feel better soon; Were all gonna feel better soonwell all feel better soon…”

(soulfulchant increases as Bronco takes hard turn down a dirt road)

Autumn: When something like killing all sixof her children made sense enough to put the kids in the Bronco and drive intothe riverI see it.

(Bronco headsdown muddy road, swerving as it increases speed)

Autumn: My memories of that moment arereally in black and white

(rear shot ofBronco revealing river; quick-cut of various angles of Bronco hitting the riverat full speed)

Autumn: Im not sure I ever met my Mom again after that point

(soulfulchant increases as camera shifts from water level to underwater; then title:LETTERS FROM GENERATION RX as bubbles float upward)

2 secondsunder black, then new music starts, amid sounds of ocean waves - video revealswaves violently lashing a minivan)

News voice: ...a strange story out of Floridathis morning, where the mother of three children drove into the ocean off ofDaytona Beach

News: The pregnant mom spoke of demons before driving intothe Atlantic...

Newsvoice: Police say theyve never seen anything like this ..

(cut toNewburgh, NY news video from Associated Press)

AP Reporter: The tiny city of Newburgh NY is trying to come togrips with the deaths of 3 young children who died when their mother drove theminto the Hudson River. . .

Nicholas Valentine, Mayor, Newburgh, NY: we are talking about a tragedy inthis city that is probably second-to-none…”

AP Reporter: It all unfolded at this boat rampTuesday evening

Fire Chief, Newburgh, NY: any effort to locate the vehicle,difficult at best...it was not floatingit was underwater.

Reporter SOT: among the victims are 2-year old Lance Pierre and his11-month old sister.

Tilda:Perhaps we should take nothing for granted: not our loves, nor our lives our familiesor friends even our sanity. One minute, all is well the next, were plunged into darkness, unable to process what isreal and what is madness.

(bronco hitswater - splash sfx)

Tilda: Autumn Stringham (String-um) realized this all-too-young.

Autumn: It was the summer after I turned eight.

Tilda: She should not be aliveand she knowsit.

Autumn: That was the moment that shattered trust. How do youtrust anybody after that?

Tilda: Forcedto confront a mystery beyond her comprehension, she spent decades haunted in search ofanswers in pursuit of peace.

Autumn:. . .when something like killing all six of her childrenmade sense enough to put the kids in the Bronco and drive into the riverI see it:gravel spitting and water flying and kids screaming. Somehow she managed to digit up to back out of thatand thats anincredible victory for somebody in that state of mind. There are other motherswho dont win that battle.

Tilda: Inexchange for this redemption, there was a price, however

Autumn:(fighting toregain composure) and its taken me thirty years....to be able to find thebeautiful side of that memory. . .

Tilda: Autumns mom did eventually die by suicide alone on acountry road. Tony Stephan was now widowed with eight children at home.

Tony Stephan: Im laying in bed at night in my roomlistening to a house full of mourning; and it just shattered the whole family.It just shattered the children, it shattered me.

Tilda: It hasbecome so commonplacethese irrational acts and horrific deedsthat weve almost become numb to it. Weve seen them in schools and public spaces .. in homesand churches. Theyre all over the news. Try aswe might to understand them, we cant. Try as wemight to ignore them .. they call to us still.

Andy Downing (Parent): We called the paramedics, they tried feverishly torevive her. And I was trying to give her mouth-to-mouth resuscitation but Iknew something was wrong because her body was cold.

Tilda: Its2004. Andy Downings world has just been shattered;his daughter, a victim of an unimaginable act of violence. But it was how this 11-year old girl died that truly horrified theworld:

Candace Downing home video: Hello, ImCandace Downing

Tilda: Candace .. hanged herself.

Mathy Downing (Parent): When Candace first died, we asked ourselves, how could we not know that she was unhappy?

Tilda: The Downings didnt realize itat the time, of course, but her case was not a rare event. No Candace was far from alone.

Nancy McCartney (Parent): He texted us .. and said, Mom, I love you and I will see you soon. He texted his dad, and said, Ill call worksoon. I love you and I will see you soon. Texted his brother, and said, I love you Hayden. I will see you soon - and then he hanged himself.

Rhonda Carlin (Parent): She started on this drug somewhere in January. Andthese things make you unafraid. They make you do things you wouldnt do normally. They make you able to put a rope aroundyour neck and hang yourself.

Linda Hurcombe (Parent): Caitlin died at home and we found her, and shed probably had been dead for maybe at the most fiveminutes when we found her. Shed hangedherself in the guest bedroom upstairs.

Kristina Gehrki (Parent): It really is like a perfect murdermystery novel. I mean, its almost likekilling somebody with an icicle and it melts and the weapon is gone.

Tilda: Theywere still dizzy from death .. traumatized and broken .. when they solved themystery. The drugs responsible, they say, are called SSRIs .. and theyre among the bestselling drugs in the world.

Rhonda: It was a sample pack. . .ofPaxil.

Nancy: Cipralex

Mathy: Sertraline, which is Zoloft

Kristina: (clip6-18:32): themaximum dose of Zoloft legally allowed

Linda: There was one thing in her systemin the coroners report: a therapeutic dose offluoxetine hydrochloride.

Tilda: SSRIsare better known as antidepressants.

intercutZoloft TV ad

Tilda:Psychiatric drugs like SSRIs have been defended with religious zeal by theirbelievers and damned by others as some of themost dangerous drugs on the planet.

Distinguishingtruth from fiction has been a challenge, and this has placed the public in theunenviable position of deconstructing the scientific and medical dogma ontheir own, in the midst of a 30-year social experiment. As Director of theNational Institutes of Mental Health, Thomas Insel has been at the center of astorm of contradictions about the use of these drugs.

Thomas Insel, MD: I think that we have to be very humble about thisright now, because weve often been soself-congratulatory, because we have, after all, many people feel, made greatstrides. The numbers dont reallysupport that.

Tilda: Dr. Insels candor is sure to shock and upset many - on allsides of the debate. The word failureis one fewhave dared to utter.

Insel: Fundamentally,why have we failed here?Why has thesuicide rate not come down? Why have the measures, disability, whatever thosemight be, why have those continued to go up instead of down? All of the numbersare going in the wrong direction, so where, where have we failed? Whats gone wrong here?

Tilda: The answers, according to Insel,run contrary to the standard arguments put forth by mental healthprofessionals.

Insel: A lot of people say its because of stigma and access. The fact is that actuallymore people are getting more treatment than ever before, so its hard for me to quite believe that. I would justsubmit that from the NIMH perspective, the answer about why weve failed is a little more disruptive. And that answeris that we dont know enough.

Tilda: Tohear the Director of the NIMH say now that all of the exultations aboutpsychotropics - from the media, from academia, from the profession, fromgovernments werenot merited isunsettling. After billions of prescriptions and hundreds of billions of dollarsin drug company profits how did this occur?

Insel: I think that our field has goingoff track here by devoting so much of its resources over the last 20 to 30years, both publicly and privately, just trying to understand how the drugswork. If the drugs were truly curative, if it was like trying to understand howinsulin helps somebody with diabetes, that might be defensible. But youve got medications here thatat mostreduce some of the symptoms of mood disorders, of psychoticdisorders. They dont, in any sense, provide a cure.

Tilda: Thischange of heart contradicts what weve been toldabout psychiatric drugs for a generation now and raises serious questions abouthow and why these drugs have been dispensed so indiscriminately to millions.

Jeri Oler (Patient): I was massively drugged. I tried drug after drug. Idid what they told me to do. I used to take tranquilizers, benzodiazepinesthats all i did was pop pills all day.

Nicole Monkman (Patient): They just kept handing me pills. Here, lets try this, Lets try this,Lets try this. And I felt like a walking pharmaceutical company,really. And nothing was working. I was drugged out. I was a nonexistent person. I had a heartbeatand thats really all that I had.

Melissa Binstock (Patient): I was just sort of given these pills and said, Swallow this. Take that. Chew this. And I was never told: Well, you might experience these side-effects,or This actually might not work. It was like they were just was given to me as like apanacea like, This is going to fix your Tourettes. This is going to fix your OCD.This is going to fix everything and everything is going to be all better.Really, as an8 or 9-year-old, I really believed that, until I began really experiencing allthose horrible side-effects that eventually changed me into not even a person,but like a monster. I was horrible.

Terence Young(Authorand Member of Canadian Parliament): Doctors, to a large degree, have abandonedtheir Hippocratic oath, which is to do no harm. That is, its like a pill for every ill. They are knee jerkprescribers, many of them. In fact, it has been shown that the average doctorwill make a decision to prescribe a drug within 19 seconds of seeing a patient.

GARY GREENBERG, Ph.D (Author and Psychotherapist):Using antidepressants, or any of the psychiatric drugs is simply notunderstood, its not explained, its not dwelt upon. I think theyre in a different class of drug from most of the drugswe take for our other ailments.

Tilda: In the80s and 90s, SSRIs were the first in a class of new mental health potionsheralded as wonder drugs and miracle cures. They were extolled as safe and effective solutions for the age-old problemof depression and were marketed as such. Thus began an aggressivemarch towards a new era in Psychiatry, one which boasted chemicals for themental health conditions that had dogged humankind for millennia. Thirty years later,however, the window on that era, and its boldproclamations, appears to be closing.

Gary Greenberg: What are we doing? I mean,especially when it comes to children, we dont really know how the drugs work, we dont know whether they work, we dont know whether theyre neurotoxic, and so that means were in the middle of a public health experiment thats been going on for the last 50-60 yearsand moreintensively for the last 30 years. And it could be that 100 years from now,theyll look back at us like we look atthe Romans who poisoned themselves with their lead pipes, saying, look at some of the effects of the widespread use of these drugs. Lookat what these people did.

Irving Kirsch (Author and Psychologist):My predictionI dont think Ill live to see itbut my prediction is, that someday, we will look back at the antidepressant era and have the view ofprescribing antidepressants that now we have of bloodletting.

Tilda: IrvingKirsch rocked psychiatry with anappearance on 60 Minutes and an explosive book, The EmperorsNew Drugs.

Three timeshe tested the data on SSRIs three times, he verified thatprescription antidepressants were no better than taking a sugar pill. Still, hewas under fire from critics who vowed to prove him wrong.

Kirsch: People started doing other studies.They said, well maybe you did your statisticswrong. Critics, opponents, they took our data an re-did it.The FDA has done its own meta-analysis, looking at all of the antidepressantstheyve ever approved. They got the sameresult. Everybody gets the same result.

(at end, showFDA Meta-analysis graphic with FDA HHS logo)

RobertWhitaker (Author, Journalist, PulitzerFinalist): I was abeliever in this story. I wrote stories about how psychiatric disorders arecaused by chemical imbalancesthese fix them. I can rememberwriting a story about depression screening day. Isnt that a good thing? Go get screened. So I was a believer in a story of psychiatry as astory of progress. We were learning about the brain, we were learning about thebiological underpinnings of these disorders, and we had drugs that fixed thosebiological problems. That is what I believed as a science writer. So I wasstunnedwhen you actually go to the research, its not there. The whole story starts fallingapart.

Tilda: As thewar of words over psychotropics intensified in the new century, journalistRobert Whitaker weighed in with Anatomy of An Epidemic and quicklyfound he, too, had a target on his back.

Pundits saidWhitaker would have blood on his hands if people stopped taking theirmedications as a result of his book.

Yet, when the Director of NIMH wasasked to evaluate Whitakers analysis ofthe science behind psychiatric drugs, Dr. Insel said this:

THOMAS INSEL, Dir., NIMH: I will take one piece of what he said to heartand I thinkits an important one. And his commentis just to observe that in spite of this enormous increase in the use ofantidepressants, antipsychotics, and other neuroleptic or psychotropicmedications, which is that broad class, over the last 2 to 3 decadesits been difficult to demonstrate a commensuratedecrease in morbidity, that is, disability or mortality, measured by suicide.Now, in other areas of medicine, if you increase the use of your medicationtwofold, threefold, sixfold, you will seewe have seen, reductions inmorbidity and mortality.

ADD SHAKERSFX for Pillsvideo

Now, we canargue about whether in those people that get the right medication at the rightdose for the right duration, there really have been lives saved. There are beenreductions in disability and every one of us has seen people who have donebeautifully, and whose lives have been saved by the use of medication. But at apopulation level, his observation needs to be taken very seriously.

Julia Rucklidge (Professor of Clinical Psychology,University of Canterbury): In the immediate, it could make a huge difference. Youcould have someone going from being psychotic to being non-psychotic, which isa pretty amazing change in behavior. But what I think what we need to recognizethat whats happened over the last 50 yearsis that they havent shown to be as good as we thoughtthey were.

Barry Turner (Senior lecturer in science, medialaw, & public administration, University of Lincoln - UK): All of these drugs are known tocreate benefit for people. All I am concerned about is that they have aninformed choice. If the public wants to take Prozac, if the public wants totake Paxil, they should have the opportunity to do so. But they should do so inan informed way.

Tilda: Yet, in the case of psychiatricdrugs, informed choice is a bit of a misnomer. . .andfinding the path of least risk can be daunting. In this vacuum, millions havebeen harmed, simply due to a lack of knowledge.

Joanna Moncrief (Academic psychiatrist and authorof The Bitterest Pills -UK): Psychiatrists knowledge and training in the areaof psychopharmacology is completely inadequate, in my view. And this is partlybecause of the focus on the disease-centered model. Psychiatrists have been soobsessed with what disease different drugs treat, they havent looked at the drugs as drugs, and they havent understood all of the harmful effects the drugs canproduce.

Julia Rucklidge:Its time for us to stop and reflect on this and say, Okay. Where are we at with the use of medications? It serves a purpose, its got aplace, but we need to also stop and recognize that there is a cost to this andthat there are people who are struggling for other reasons now because of theside effects associated with these medications.

Nicole Monkman (patient): I was on Seroquel, Lithium,Clonazepam, Imipramine; Ive triedevery antidepressant, every mood stabilizer, every antipsychotic,Benzodiazepines. I mean, do they tell you that its six days or something very minute for thoseBenzodiazepines, because theyre soaddictive? They dont tell you that. Then, they say intwo weeks, your anxiety is higher so here aresome more pills. You try coming off that stuff. Its worse than,they say, than coming off of heroin. Its hellits hell.

Melissa Binstock (patient): One of my best friends is bipolar,and she has been medicated her entire life until about three or four years ago.And we talk about it. We have horror storieswe swap them, you know. [Laughter].Its almost a competition like whosecould be worse? Ive got some pretty awful stories,but so does she. And I feel its prettycommon among people that have grown up being on pills.

JenniferKinzie (MentalHealth Counselor): My first main position in my field, the human services fieldwas in a group home, and these youths were on 5, 6, 7 medications. They wouldbe on Risperdal and Seroquel, they would be on Paxil and Zoloftit was justan incredible amount of poly-pharmacy that took place. So I can have empathyfor those who dont get it, because I didnt get it.

Tilda: Toomany times, injured parties say, they were greeted not by empathybut by apathy instead. They report being ignoredby the regulatory agencies, law enforcement, elected officials, and worst ofall, by their doctors and the medical community as a whole.

LEAVE SLIGHT SPACE - TOO TIGHT

Victims ofviolence, suicide, and a host of other serious adverse effects were dismissedas anecdotes and told that their experiences were attributable to the diseasenot the drug.

David Healy,MD (Psychiatrist,psychopharmacologist, scientist, and author): When I treat you and put you on apill, lets say you turn blue, and then we halt the pill and you turn back to yournormal color. And then we put you on the pill again and you turn blue again.Until very recently, everyone would agree that that was a convincingdemonstration that this pill caused at least you to turn blue. Now weare told that thats an anecdote. It didnt happen.

Tilda: While the drug companies ruthlesslydefended their magic bullets in the Courts and through the Press, they were, ineffect, stigmatising people who were harmed by using them. The long lens ofhistory has revealed that the troubling effects of these chemicals were well-known - years before FDA and other regulatorybodies actually approved SSRIs.

cg: FDA PROZAC HEARINGS, 1991

Pallie Carnes: This is hard for me because I tried to commitsuicide in front of my five children

Irene Dotson: I attacked him with a kitchen knife

Debra Douglas: I took the 9mm automatic, sat down on the bed andput the gun to my head.

TuckerMoneymaker: After being on Prozac for 21 days, my wife shot andkilled both of these two boys right here

Pallie Carnes: Eli Lilly calls Prozac the wonder drug and I wonderwhy? Thinking back on how this drugaffected me, does a wonder drug rob you of a conscience? Does a wonder drugmake you forget the difference between right and wrong?

Peter Breggin,MD (psychiatrist and author): In the early 1990s this issue had reached a peak, Was Prozac Causing Violence and Suicide? But whathappened was that their psychopharmacology committee, almost everybody on thecommittee worked for the drug companies. So the conflicts of interest was soenormous that the FDA had to give them all letters forgiving them of theirconflicts of interest so they couldnt be sued.

cg: 1993

Kevin P. Miller to FDA Chief (1993): What about your concernregarding Prozac? It is very well documented: 28,000 adverse events, 1600suicides associated with that drug.

Michael R. Taylor,Deputy Director, FDA: Well, drugs that go through our very rigorous testingand review process are very well understood chemicals. And drugs are recognizedto have both risks and benefits, thats why they go through a rigorous evaluation, and whenthose products are put out on the market, we have a good scientificunderstanding of both the risks and benefits. Thats laid out in very detailed labeling that physiciansthen use to decide whether to prescribe those products to their patients. Sideeffects are part of pharmaceuticalsthats recognized, and thats why were socarefully scientifically.

Peter Breggin,MD: Well, nothing could be further fromthe truth that the chemical is well understood or that the FDA was careful.Actually, what the FDA was careful about was to consciously cover-up everyreally dangerous adverse effect of Prozac.

FDA employee: Kevin, this wasnt on the list of things we were supposed to talk about(interrupted by other FDA employee)

Michael R.Taylor: Why dont you turn the camera off so we can talk?

Breggin, MD: They did nothing, absolutelynothing. Meanwhile, Eli Lilly was busily hiding everything they could about theincreased rates of suicidality.

Karen BarthMenzies: It was amatter of how do we cover it up? How do we hide it? Every step of the process,towards approval and marketing thereafter, was designed to hide and mislead thepublic and physicians about the suicide side effect.

Andy Vickery (Attorney and Patient Advocate):Leigh Thompson, the chief scientist at Lilly writes in February 7, 1990, thathe had a conversation with Dr. Paul Leber at6:15 in themorning. (show document with digital typingsfx) Now, thinkabout that. You work for the United States government, the taxpayers of theUnited States government, and your job is to be my watchdog. Do you think Im going to call you at 6:15 in the morning?

And oh, bythe way, if you want to send me something, Ive got this special back line overhere at the FDA. Send it through backchannels, you know, so other people dont get itjust feed me this info on the QT. Itsextraordinary.

Tilda: Lillys own secret files implicate the FDAs Paul Leber,Robert Temple and Thomas Laughren as being complicit in a scheme to whitewashthe dark facts about Prozac.

Karen BarthMenzies (atty): Thereare some verytelling documents that show the cozy relationship between FDA officials and EliLilly in those early years, in the early 1990s. Lilly employees or Lilly personnelreferring to certain members of FDA as our friend in the FDA. Theyre our defender.They wereworking hard to get over this suicide issue and they referred to the suicideissue as a public relations problem.

MUSIC BRIDGE: COMMONSENSE

Tilda: By1997, Prozac had become Americas mostreported drug to Medwatch, with over 39,000 serious adverse-effect events onfile. Since only 1% of the actual number of events are reported throughMedWatch, this means that nearly four million people in the US alone hadalready reported experiencing mania, anxiety, agitation, hostility,hallucinations, suicidal ideations, and more.

Breggin, MD : when youre working on these things and you find this out, youthink to yourself what what kind of world are weliving in? That theres so muchsleight-of-hand and manipulation and fraud going onto deceivethe American public and the world from the fact that drugs are causing peopleto kill other people and to kill themselves. It is astonishing.

Tilda: EliLilly has been called The House That Prozac Built. Before the drug was introduced, Lilly reported earnings of $600 millionannually. Prozac changed Lillys fortunes and thecompany banked at least $21 billion dollars in profits from the drugover the life of their patent.

music rampsup; fade toblack, title appears:

Sara, Brennan, and Gods Coroner

MUSIC: ANJA SINGS: I GUESS IT HAPPENED ON PURPOSEBUT LATELY THINGS HAVE BEEN GETTING QUITE INTENSE

TerenceYoung, Member ofParliament, Ontario, Canada: When I say to some people, prescriptions drugs are the fourthleading cause of death in our society, that seems to be the dividingline. Theres some people who already know its true, who have read about it and understand it. Thentheres others who think, Oh, thats a myth. That cant be true.They simplycant conceive of that, so they stoplistening.

Tilda:Terence Young is a Member of Parliament in Canada, serving Oakville, Ontario,just outside of Toronto. After a prescription drug caused the death of hisdaughter Vanessa, he founded an advocacy group, Drug Safety Canada.

Terence: Vanessa collapsed in front of me.Her heart had stopped, basically as she stood up to go upstairs. When you losea child your world is upside down. I was thrown into a study of medicine, ofmedical jargon, of how the health care system works and when it doesnt work. And I didnt ask for it, but it was my way of dealing with theloss of Vanessa. It was, in a sense, my way of grieving. It started the day shedied.

Tilda: Forfive years, Young investigated the practices of the medical and drug industries.And in doing so, he says, he realized how Pharmas influence had permeated every construct of modernsociety.

Terence: They find a way to create afinancial interest in every institution in our society that we rely on forcritical thought. They have money in our universities, in our colleges, in ourhospital boards, in the media and they almost always win.

Tilda: Theloss of his daughtercoupled with the shocking truths he uncovered throughhis medical research led him to write Death By Prescription and become one of Canadas most ardent proponents of informedchoice.

Terence Young: Glaxo SmithKline just paid the largest fine in thehistory of the United States related to fraud and criminal acts for a drugcompany. They paid 3 billion dollars for illegal marketing of Paxil, Wellbutrinand AvandiaPaxil and Avandia both having beendrugs that caused a lot of deaths due to adverse drug reactions. And they paidit in cash.

SUICIDE 2MUSIC

James Cole (Deputy US Attorney General):This action constitutes the largest healthcare settlement in United Stateshistory.

TerenceYoung: It was intheir business plan. Because those three drugs, in the years involved sold $25billion dollars worth. And the drugs are marked upin the thousands of percent.

Carmen Ortiz (U.S. Attorney-Massachusetts):GSK distributed Paxil with false and misleading labeling. What GSK did wasencourage the use of Paxil for children who are dealing with depression withfalse messages about safety and effectiveness.

DanielLevinson (InspectorGeneral, Health and Human Services): This unlawful promotion putchildren at risk of taking drugs that were unproven to be effective for them,and have been shown to increase the risk of suicide.

Tilda: Thesefraudulent practices were locked away for decades protected byinstitutions and doctors and the drug companies themselves. Psychiatric andscientific ethics were cast aside in exchange for profits - no one went to jail- and real people paid the price.

fade to black

NancyMcCartney: Brennan worehis heart on his sleeve. He just adored social situations. He loved to singfrom a very young age, music was part of our life and part of what he adored.To the point where one of the nicest memories we have, was he was at Peggys Cove with his aunt Meryl and decided at the giftshop that he would sing Danny Boy to all the senior citizens on thebus tour there. He just broke out into song and had his own little audience atPeggys Cove.

music: Oh, Danny Boy. . .oh, Danny boy. . .

Shaun McCartney: Yeah, what I miss most aboutBrennan is when he came in, hed always giveme a hug. Hey dad, howre you doing?Give me ahug. I still think to this day that hes going to walk through the door. We were driving, nottoo long ago, and it was Nancy, myself and our other son Hayden and I looked in the back seat andHayden was sleeping and I looked to see if Brennan was there. Just out ofhabit, to see if he was sleeping too.

Nancy: I saw Brennan walk out of thishouse, he was very robotic.

(a dreamlikereenactment - blurry - medium shot of Brennan murmuring as he puts his coat andhat on) -Nancy:Brennan, where you going? - Its okay mom, I just got to go. Puts on his winter coat. Brennan,its hot out today. - Its okay mom, I just got to go. Puts on his winter hat. I said, Brennan, its hot out today you wont need that. - Its okay mom, I just got to go. I said, well, I need you here for a minute. - No, its okay mom, I just got to go.Thats all he could say to me, and this was a child who wasvery articulate, who was so verbose that sometimes you would just say okay, okay, enough, enough already.

Tilda: Fourdays prior, Brennan went to the family doctor with a chest cold andinexplicably came home with a sample pack of the antidepressant Cipralex. Atthe time of his disappearance, he was exhibiting the classic signs ofAkathisia.

Shaun: When Brennan went missing I drovethe roads for hours just north of here. And I did every side road, everyconservation area, every laneway looking for him. One of the things that hedidnt have was a great sense ofdirection. I thought maybe he had gone for a hike in the bush and got turned aroundand couldnt find his way out, and I wentlooking for him. Thats what was going through my mindthe whole time.

Nancy: He texted us and said, Mom, Imsorry. Im sorry I was mad about the cat. I love you and I will see you soon.He texted hisdad, and said, Ill call work soon. I love you and Iwill see you soon. Texted his brother, and said, I love you Hayden. I will see you soon and then he hanged himself.

Shaun: When Brennan went missing, I hadno concern about him having taken his life. None. None whatsoever. Because itwould have been the farthest thing from my mind that that happened. And it wasnt until I was standing at the door and the coroner andsix other people walked up to the door, that I knew Brennan had passed.

Nancy: Weve lost part of our hearts and they say theres no greater pain than losing yourchild. And I believe it. I let him go out thedoor and that was the last time I saw him alive. And he bought his rope from alocal store and drove to a conservation area .. texted us .. and then hangedhimself. Thats when hell started.

Shaun: For me, after that point in time,as a parent, I struggled with it greatly. I looked for signs for things that Imissed. Things that I should have seen, that was my responsibility as a parent.

Tilda: All of Brennans teachers, friends and teammates struggled too. Why was there no sign? they asked. Some warning? But none came.

Nancy:Brennans friends, his teachers, were allsaying, how come we didnt know? We were out for dinner withhim on Saturday night. Why didnt he talk to us? For them, they all felt they had let him down, when infact, it was the drug that caused his suicide.

Tilda: Beforelong, other teens across the Canadian province of Ontario were dying, just likeBrennan did. For Terence Young, the problem hit close to home again, whenfriends and constituents faced the same horror he and the McCartneyshad.

Terence: My wife called my son Hart to thephone and we heard him say a few words and he banged the phone down and ranupstairs, obviously quite upset. We went to him and said, What happened? He said, Sara Carlin hanged herself. And we met Sara, who was 18 yearsold just a few weeks before on our back deck, they were part ofthe same social group in Oakville. Theyd play guitar and sing songs and do karaoke.

Sara karaoke clip

Terence: Because of my own research thefirst thing I thought about when an otherwise healthy young person dies is, Was a prescription drug involved? And of course it was. In fact,there is no doubt in my mind that Paxil and withdrawing from Paxil was thecause of Sara Carlins demise, her suicide.

Rhonda Carlin: She started on this drug somewhere in January. Andthese things make you unafraid. They make you do things you wouldnt do normally. They make you able to put a rope aroundyour neck and hang yourself.

Terence: A young woman hanging herself is anextremely rare thing to happen. She went home one Saturday night at two oclock in the morning, took off her makeup and hangedherself in her parents basem*nt.

Neil Carlin: I reached out to Terence at onepoint because I was in contact with the Coroners office. I was starting to put the pieces together.It wasnt until after Saras death that we actually started to connect the dots.Were bereaved fathers, we have agreat connection and with Terences help, wegot the inquest.

Rhonda: The doctors wouldnt talk to us after. We fought hard for an inquestbecause we needed to understand, and after Sara had died,then we started doing research on the drug. Thats when we really found out about the drug. Thats the first time that we realized that Paxil, one ofthe side effects was suicidal thinking.

Neil: Everyone told us its not going to happen—“Youll never getan inquest on a prescription drug. So it goes to show you what acouple of Dads can do.

Terence: I worked with Saras dad, Neil. We pushed very hard to get an inquest. Iasked as Chair of Drug Safety Canada to be party to that inquest and Iwas turned down. But the coroner did allow me to be an expert witness on drugcommunications, which I did.

Rhonda: Theres a videotape of the coroners counsel saying on the very first day of the inquest,We will show that Paxil did not play a part in SaraCarlins death. Well, the whole point of the inquest was to see whetheror not antidepressants played a part in Saras death!

MichaelBlain, Attorney representing Ontario Coroners Office:Courtsacknowledge that this medication can increase thoughts of suicide in particularpatients, but they dont think the medication played arole in Sara Carlins death.

Tilda: TheCoroner in Ontario resisted every request by the Carlins to get the truth aboutthe death of their daughter but the Carlins were willing torisk everything to get it.

Rhonda: We basically mortgaged our hometo the hilt to try and get some answers, but to me, it was worth it to havethat doctor up on the stand and the question was asked, our lawyer asked him, Did you tell Sara that Paxil might cause her to want to kill herself?And he said, No, I didnt. Why didnt you tell her that? Because, he said, she wouldnt have takenit. Did you tell her parents?No. Did you tell anybody? No.

Neil: Coroners see the suicides; investigatethe suicides. Coroners dont want to doanything. Coroners are medical doctors. The coroners are the first line ofdefense for the industry.

Tilda: And at the inquest, the odds werestacked against the Carlins.

Rhonda: The jury, I think, was verycourageous. But they were specifically instructed by the coroner that theycouldnt actually find Paxil as a cause.

TERENCE: The jury made 12 keyrecommendations and six of themthese were detailed recommendationsto prevent similar deathssix of them were aimed at the drug industry and thedrug company. So if they didnt think thatPaxil caused or played a critical role in Sara Carlins death, they certainly wouldnt have put six recommendations aimed at the pharmaceutical industryin their decision.

Tilda: As wasthe case with Sara Carlin, any questions about possible links between theantidepressant Cipralex and Brennan McCartneys sudden death were quickly rebuffedby the Ontario Coroners office.

Nancy McCartney: We met with the coroner privately about a monthafterwards and at that meeting it was just sort of niggling in the back of ourminds: Is it possible that this medication, the only new thing in Brennans life, is it possible that thiscould have caused his death? The coroner, the investigating coroner, quickly saidno. . .

Shaun McCartney: My thing is, they wont even consider it. So Im saying to myself, if that happened to our son, howmany other people havent they documented, havent they tracked? Theyre saying statistically that not that many people areon the drug.

Shaun: And theyre saying, they havent recorded it. Nobodys recorded that. If we hadnt kept pressing and kept pushing that envelope withthe coroners office, none of this would bedocumented. None of it.

Nancy: Before Brennans death, I would have said, Oh, no, they are doing their best, and we feel very let down by them.They have not looked at Brennans deathobjectively, and Brennan doesnt have thejustice that he needs.

Rhonda Carlin: It took me a year to get the strength to write to theChief Coroner. I said, It came to my attention that you, in fact, had thecause of death changed. Isaid, How can the coroners office have such a lack oftransparency? I received a letter back basicallytelling me that it was criminal offense to meddle with the jury. If I didnt stop meddling I would be charged and put in jail.

Terence: I believe where we are right now,those of us who understand the true risks and have been trying to warn othersand make change, were at the bleeding edge. Not theleading edge, because the leading edge hasnt even started yet. Were at the bleeding edge, were the ones they think who have sort of lost it. Iknow drug reps have been telling people in Ontario for years, oh this poor guy lost his daughter, hes lost his mind, hes exaggerating stuff. Then theres others thatrealize Im not exaggerating. In fact, theevidence backs it up. My book has 200 footnotes. Its totally evidence based. Ive never been challenged. Ive never been threatened with a lawsuit. The hurdle istrying to get people to believe that is something so unbelievable.

RHONDA:Im gathering my strength. I haveboth letters, and I didnt meddle, butit came to my attention and I know it happened. I guess Im to the point now where I am so beaten downif you wantto put me in jail, go ahead.

Nancy: Our mission, per se, is to bevocal about this, because if it saves one life, then its all worth it. As much as it, every time we talk aboutit, it re-traumatizes us, makes us relive the experience. But it is whatBrennan would have wanted us to do.

end withDanny Boy and pastoral view of Ontario lake

HEALTH CANADARx DRUG ABUSE AD: Last year, over 80,000 Canadian kids used Prescriptiondrugs to get high, even though it can be very dangerous. Talk with your kidsabout prescription drug abuse.

LEAVE 1-2 SECONDS MORE SPACE BEFORE TITLE:
UNDER SIEGE

KPM: Were you 240lbs of fury?

Joe Stephan: Oh Goodness, yes. And I was not easy to deal with.

Tony Stephan: My son Joseph at that time was 15years of age. Extremely ill.

Joe Stephan: It didnt matter what it was

Tony Stephan: very very violent

Joe Stephan: the drop of a pin would set meoff

Tony Stephan: You could actually say he wouldbe everything a schoolyard shooting was made of.

Sfx:911-wheres your emergency?

Tony Stephan: he was diagnosed with bipolareffective disorder 1

SFX: enginenoise from Bronco -video ofBroncoaccelerating -

Tilda: In the years after Debbie Stephandrove the familys 1990 Bronco into a raging riverwith her children inside, the mental states of both Autumn Stringham and herbrother Joseph Stephan deteriorated.

Tony Stephan (father):They didnt understandwhat their Mother was going through, that would take her to that point whereshe would be prepared to remove herself from this lifebut all thechildren with her.

Tilda:Whether the cause was genetics or sheer trauma, they both were diagnosed withbipolar disorder just like their Mom.

Tony Stephan: I was very very down. You begin to lose hope becausetheres no joy in life at all. Theres no happiness to be found. And that was the state ofour family.

Tilda: Joseph, in particular, seemedheaded for disaster.

Autumn: He was just a sweetheart, but,boy, when he hit puberty, he really went over, and became incredibly manic andincredibly violent in his mania. He was scary. My dad was scared.

Tony Stephan: Joseph was medicated with lithium. I believe he wastaking 750 milligrams of lithium and he was up to 900 milligrams of lithium fora period of time to try and control it. . .

Joe Stephan: Was I having huge mood swings? Yeah, that stuffdefinitely started. Id been through a lot of pain withthe death of my mother and various events that happened in my life. After mymother had committed suicide, I was the most violent person that i knew of. Iused to wander the streets at night and Id go pick fights with the local people and I had thisaluminum bat Id found and I beat it against thecurb. It was jagged and torn upand that was my weapon of choice. Im lucky I never touched anybody with that thing, butthats where it was headed. It wouldnt have been very long before something actuallyhappened.

end with Joe-filmed from behind- yelling Hey, get back here…” -

Tony Stephan: My children were already saying to me, Come on dad. Youve got to gethim out of the house. Hes going tokill somebody. Youve got to dosomething, Dad. It didnt matter whatwe threw at this situation, it wasnt going toget better and Im going tolose him to a suicide, or hes going tohave to be institutionalized.

Tilda: Athousand miles away, Autumn was also struggling desperately. Now married with achild, she, too, was caught in the grip of her mothersmadness.

Autumn Stringham: At that point in my life, I justfelt like everything was ashes. Id just lostmy mom to suicide. My diagnosis had been upgraded, so now I was rapid-cycling bipolar one with schizophrenic tendencies, which was it seemedreally dark, like I wasnt going toget over that. And so I had actually planned to commit suicide.

Tilda: Withone child ingesting a five-drug co*cktail and contemplating suicide and theother engulfed by violent thoughts, Tony Stephans family was under siege.

Tony Stephan: My daughter at the same time hadbeen in and out of the psych ward, struggling with the same issues as hermotherand her brotherand was on five differentmedications. She had been through majormedication changes. It wasnt working. Atthe very, very best, it wasntworking. So, I was left in a terriblestate, a terrible state where I had to find an answer, because you see, myfamily was literally coming unglued before my eyes. I was going to lose myfamily.

Tilda: Besetby grief and confused by the cruelty of his circ*mstances, he began to look foranswers .. some way out of this madness.

Autumn: Sheer and utter desperation.

Tilda: It wasa journey that would reshape his life forever.

Autumn: He started studying everything thathe could about bipolar and recognizing a lot of the patterns that hed seen with my mom in all the years that theyve been married, and I think it really helped him tosee that the needed to do something about it.

Tilda: Dosomething but what? The experts had all weighed in: both hischildren were spiraling into the same orbit as their Mom and there seemed little hope hecould save them. But Stephan resolved to find an answer and preventany further suicides in his family.

cg:O What a Tangled Web We Weave

Nicole Monkman: I was at the bottom of a pit. I had many differentpsychiatrists, many different hospitals, many facilities that I had to go to.And they just kept handing me pills. I wouldnt call it angst, I would just clearly call it hell. How could such abeautiful thing of life, giving birth, cause such trauma?

Sonya: I just remember being veryunhappy, very sad and hopeless. I neverthought it would end and just saw no way to get out of it.

Jeri Oler: The drugs made me completelyemotionless; they made me not care; I didnt care about anything around me. The only thing i sawwas my pain and the drugs made me numb to anything else.

Melissa Binstock: I was diagnosed with Tourettes Syndrome. So, um, in order to treat the TouretteSyndrome, I was put on medications.When I waslittle, I would just have these really violent mood swings and panic attacks,insomnia, hypersomnia; there were periods where I couldnt eat, there were periods I would eat too much. So,all of these really confusing things were happening to me and I, at that time,didnt realize that it was because ofthe medication that I was going through all these horrible changes.

CathyBinstock (mother): I will probably never get over thehorrible guilt and the horrible I think that part of her childhoodwas stolen from her.

MB: They began to basically just forceme to take the medication which made me feel as though I had been betrayed byabsolutely everybody, because I felt as though they were giving me these toxicthings that were making me sick and violent and horrible.

Cathy B: I didnt know by her not wanting to take the medicine thatshe was really trying to say to me You know what? This isnt workingbut whateight year old can verbalize that? The psychiatrist kept saying to me She needs this. She has to have this and the psychiatrist was our family friend and I trusted him.

MB:(4:20) Theycompletely put their faith in this particular psychiatrist who I dont think had my best interests in mind at all.

Nicole: My doctor decided that electricshock therapy would be good because I was drug-resistant. We had tried for almost a year. Hejust kept saying, Well try more drugs. Well give you this. Well do this more shock therapy. Well, really? How much more can mybody take? I was 100 pounds and dying. I literally was dying.

LEAVE SLIGHT SPACE

Sonya: my psychiatrist decided thatelectric shock would be the next step, so I did a series of eight sessions ofthat.

SLIGHT SPACE

The ECT was ahorrible experience. I loved going to school and learningI had to dropout of school. I really couldnt do thethings in life that Id always done and wanted to do.

Jeri: For about 16 years, I washospitalized every year for about three months. Finally in the last five yearsof my illness, I said, No more. If you ever take me to the hospital again, Iwill kill myself.

Melissa: When my mom would call him, sort offrantic, Melissas having a reaction, or Melissas having an episode of violence,or Melissas hurtingherself, he would say, Make her take the medication!

Cathy B: The Psychiatrist said If she doesnt listen, andshe doesnt want to take the medication, youjust call 911 and go over and visit the psych hospital because thats where shell go.

Melissa: Gosh, Ive got a list of like 20 different medications I wason by the time I was about 11. We just had bags and bags full of pills andpills, in massive doses that no child should have been prescribed.

Bob Binstock (father): It got to the point where theyprescribed Haldol where I got really more concerned than ever.

Melissa: My mom and my sister basically foundme in the game room sitting on the floor completely zoned-out. I just rememberthis feeling of, "I'm going to die, I'm going to die, I'm going to die."

music break: Anja Øyen Vister

“…and if she falls, there will be noone there to catch her .. when she falls, there will be no one there to catchher .. and Hold On to ..

Cathy Binstock (mother): Melissa ended up in the emergencyroom. She had a very serious psychotic reaction.

Melissa: I was like, Oh, this is it, I've completely gonecrazy. This is insane. I don't know who I am anymore. I don't know what I'mdoing anymore.

CathyBinstock: I called mypediatrician and he was there in ten minutes and he said to the nurse, Get her off of that sh*t. Thats what he said.

Melissa: It was a very very low point, andwas often the case that I would contemplate suicide just because i didnt know who i was anymore and all these side effectsthat i as experiencing were so scary.

Cathy: You dont give a 9-year kid Haldol.

Anja Øyen Vister music carries out for 5-7seconds

Tilda: Asmillions filled their psychotropic prescriptions most without anything resembling sound medical advice other darkand troubling events kept occurring .. without a whisper of warning.

Andy Vickery (Attorney): If youre thinking about taking a psychoactive drug, bear inmind that the pill youre taking may look little, but itis designed to alter the chemistry of your brain in a way thats specifically intended to affect your mood and yourbehavior; to affect the very chemical, serotonin, that affects judgment, andaggression. So youre taking something that can turnyou into a monster.

GARY GREENBERG (Author and Psychotherapist):These drugs have been sold as the equivalent of insulinfor diabetes or aspirin for a headache. The problem is, when youre told that, you dont quite grasp that what youre really doing is youre changing your consciousness. Youre changing the way your mind works.

Andy Vickery: Its hard for any of us to accept the notion that a drugcould make me do somethingreally anything that I dont want to do, but particularly something thats completely contrary to my personality and my moralsand my values. You know, it could make me kill someone.

(audio sfx) Phone rings: 911, wheres your emergency?

Woman: Theres been a student shot at WestsideMiddle School.

911 Operator: Theres been what?

Woman: a student shot at Westside MiddleSchool

911 Operator: ok.

Woman: we need an ambulance as soon as possible

911 operator: do you know who done the shooting

Woman: no, we do not.

RobertWhitaker (Journalistand Author): Everytime we get one of these horrible killings, mass murder, some will takeadvantage of that to say, look, we needmore forced treatment.

What wereally need to investigate is what role are psychiatric drugs playing in suchmass killings? Are people coming off drugs? Are they on the drugs andexperiencing akathisia? And theres plenty ofevidence in the research literature in the way that psychiatric drugs canactually lend themselves to violent actions. One, You can have thisinner-agitation.

Two, Comingoff, you can have a worsening of symptoms, and the third part is, these drugscan diminish frontal lobe activity, the very part of the brain that when youget a really bad idea like taking a gun and going into a schoolthats the part ofyour brain thats supposed to kick in and say, thats a really evil idea dont do it. But these drugs will diminish that activity.

Terence Young (Member of Parliament, Canada): Every time there is some bizarreact of violence in the United States or Canada, like a school shooting or massshooting, it is so difficult to find any mention if the shooter was onantipsychotics or antidepressant drugs.

And yet inevery case Ive been able to find, the personwho was shooting was either on an antidepressant drug or had recently withdrawnfrom an antidepressant drug. And so there is some real correlation which no oneis properly investigating.

Robert Whitaker: Why have we never had a good investigationwhy? Because obviously, if we found there was anassociationtime and time againthat would be another thing that would really crimpthis commercial activity. Which tells you there are powers-that-be who dont want that question investigated.

fade to black under cacophony ofnews reports and audio - for 2-6 seconds - as it finally fades, we hear:

Kevin P. Miller: What are some of the things in the profession in the treatment of these mentalhealth conditions that you think are working exceedingly well right now?

GaryGreenberg: Uh, well, Im not sure ifthere are any. I mean, theres nothing inthe literature that would indicate that any kind of mental illness isresponsive to any particular treatment with any kind of strong signal.

Tilda: Aspart of the research for his book called The Book of Woe, Gary Greenberg was imbedded withpsychiatrists as they debated the new edition of the Diagnostic and StatisticalManual of Mental Disordersthe DSM-5.

Greenberg: All along, its been clear that the DSM is essentially a work offiction. Its the way psychiatrists have ofsaying, If there are mental disorders, ifthey exist in nature the way that illnesses like Diabetes exist, then these arewhat they are. Changing theway we understand ourselves, is intimately related to the development of theDSM.

LisaCosgrove, Ph.D (Associate Professor, University of Massachusetts, Boston; co-author, Psychiatry Under theInfluence): The DSM is often referred to asthe Bible of psychiatric disorders. It is the quintessential diagnosticinstrument. Over 400,000 mental health professionals in the United States usethe DSM, and in order to get 3rd party reimbursem*nt, one has tohave a DSM diagnosis. So the DSM is extremely instrumental.

GaryGreenberg: and so, when anyone from the outside questions it or someone from the insidequestions it too directly, the usual thing is to repudiate them.

Tilda: In 2005,two respected academics, Lisa Cosgrove of UMass-Boston and Sheldon Krimsky ofTufts, released their investigation into conflicts-of-interest between DSM-4panel members and the pharmaceutical industry.

LISA COSGROVE: I think the data really speak forthemselves. The strongest statistics include the panel members for the mooddisorders and schizophrenia and psychotic disorders. A hundred percent of thosepanel members and yesthats rightevery singlepanel member has financial associations with the pharmaceutical industry.

Wall St/Stockexchange/Pharma logos

And if youlook at it in terms of the sheer amount of money, the antidepressant market andthe antipsychotic market are the fourth and fifth leading therapy classes ofdrugs with annual sales of 20 billion and 14 billion respectively.

SheldonKrimsky, Ph.D (TuftsUniversity): You know, the argument is well were getting the best people; thebest people are consulting for the industry, and therefore, the concept ofdisinterestedness is completely destroyed. And its a self-fulfilling prophecy. If you set up the systemso that you permit people with conflictual relationships to be on committeeswhose decisions will have financial impacts on an industry, then the wholething is running on its own cycle of self-interest.

LISA COSGROVE: The problem is that they couldleverage their prestigious position on the DSM into very lucrative consultingcontracts and really influence prescribing habits.

NEED MORE AUDIO SPACE

So there are170 DSM panel members. That is the total inclusive of all the working groups.Of those 170 panel members, 56 percent had at least one financial associationwith a pharmaceutical company.

Tilda:Embedded with the new DSM-5 working committee, Gary Greenberg found himselfcaught in a firefight of words and passions over the future of psychiatry.

Greenberg: When the DSM is revised, there arefights, and in this case, intense fights, because there was an attempt on thepart of the American Psychiatric Association to finally come up with the DSM to end all DSMs.

JeffreyLieberman, (fmr.Pres. of American Psychiatric Association): Now you cant expect to revise a staple like the DSM for the firsttime in 20 years without experiencing some glitches, and believe me, we hadmore than our share.

Greenberg: It was like being in the middleof a war

Jeffrey Lieberman: But the APA kept our composurerallied when attacked by our enemies, and occasionallyby our friends, too, to make the DSM a resounding success.

Greenberg: and, uh, it didnt work. They failed and they found it very difficultto walk back from all the promises that theyd made. And the people that took them on werent the Scientologiststhey were psychiatrists. One of them, in fact, hadwritten the last DSM.

begin music, Kaval Siri

Tilda: Thispolitical infighting left millions of consumers with psychiatric diagnoses inlimbo. The DSM decision-makers may not considered that. . .but their actionsover the last 30 years have reverberated . . . in sad and profound ways.

Kevin P.Miller: Pretendthat Im the Glaxo CEO. What would youlike to say to me?

David Carmichael: [Long Pause-then Laughter-then sigh] - total=22seconds

Tilda: ForDavid Carmichael, there are good reasons why this is is not an easy question toanswer.

GillianCarmichael: My Dad and Ihave always been really close. Both my parents did everything for my brotherand I. If there was a sport we wanted to pick up, or if there was something wewanted to do, we did everything. My dad built my brother a half pipe in ourbackyard and it was like a professionallybuilt half pipe. This thing was phenomenal. We hadkids from all over the neighborhood come there to ride it because it was huge.

DavidCarmichael: Theres nothing more exhilarating than being a Dad. Ineverything Ive ever done, it was magicalmoments. Our daughter, Gillian was born in 1990, and our son, Ian was born in1992. And both my wife and I took a nurturing approach to parenting. They didnt get everything they wanted, but they certainly had alot of opportunity when they were young. It was wonderful.

Gillian: My brother got into dirt jumpingas well, so my Dad built my brother a dirt jump at our cottage. My brotherwould just spend hours out there and he loved it. . .

David: I remember the deliveries likethey were yesterday. I remember the snowstorm I had to get through when Ian wasbeing delivered in 1992. It was December the 14th thats when Ian was born. I got a call at the organizationI was working at, got home, got in the car. He was [laughter] rushed right in the delivery room.It was a very quick delivery. Gillian took over 20 hours. Ian was very quick.

Gillian: We were the ideal family on theblock and I had a lot of friends who just would continuously tell me that thatwe were a perfect family.

Tilda: TheCarmichaels perfect family began to unhingeshortly after David began taking Paxil.

David: I really didnt know very much about mental illness until when I was45 years old, and I had my first major depression. And I was treated with Paxiland in fact, when I look back on it now, theres no question I was a manic when I was on Paxil forthe first time. That was the very first time that I ever even looked at theissues around drugsand side effects of drugs.

Gillian: Well, I noticed that there was abig difference before he was taking the medication and then while he was takingthe medication. I remember him snapping on me about something very small and Iremember him spending so much time at his office. I remember him being morequiet and not being himself and looking stressed out and just looking different.

David: When I went to the doctor I was prescribedPaxil. And I had gained a fair bit of weight, i had sexual dysfunction issues,and my resting heart rate was higher. And there was just this tremendousdiscomfort with being on that particular drug. It really made me wonder, should I be on it?

Tilda: Likeso many who tumbled into the world of antidepressants without forethought,David Carmichael did so unaware of the potential dangers.

David: When I was on Paxil, we had noidea it could trigger delusions,

none of thatwas out in the public domain. For so many years, I just assumed my doctor knewbest. I learned about the side effects the hard way.

Paxil Ad RE: SIDE FX

Gillian: When everything happened, I hadjust finished Grade 8 and for my friends, who knew my father, they just knew thatsomething was wrong, because they knew who my dad was. And you just would neverin a million years think that he would do something that he did.

begin Kaval Siri

David (with red eyes): Yes, parenting wasa high priority of mine to be the best parent possible. And to have it end thiswayit was pretty devastating.

Tilda: DavidCarmichael had been on 60mg of Paxil for two weeks when he and Ian set out forone of their favorite father-son activities: a BMX bike competition in London,Ontario.

Kaval Siri as b-roll of some awesome jumpsilhouetted by the sun - dissolves into bright sun - then WHITE with screams ofjoy trailing off..

Kim Crespi: What Ive learned in this journey is that i no longer

END KAVAL SVIRI

take forgrantedeven one breath. Things get reducedto the minutesand you know you have the strengthfor that minute.

video: Crespi girls singing, its a whole new world…”

Kim: David and I were friends incollege. We were both accounting majors. David was that funny, brilliant guythat you always wanted in your group.

Peter Tonon: David was a guy youd want to be around. Thats about the best way to explain it. When you met him,he was gregarious, he was open, he was funny; he was very witty.

JessicaCrespi: My dad wasa very caring Father; very funny, too. Hed wake me up singing whatever group i was into at thetime: it was Spice Girls when I was little

Kim Crespi: Hes a brilliant auditor. Auditing for a majorcorporation is stressful and theres a lot of things that go with it if you do the rightthing.

Peter Tonon: David was a guy, like any of us,had his challenges in life we all do. Especially in a big financial company,theres stresses in our work; we havekids to raise, bills to pay.

Kim: We went to the psychiatrist inearly 2006 and he said, well, whatabout Prozac?

David Crespi: You have a chemical imbalance.Lets put you on Prozac.

Kim Crespi: Its the standard of care. Its what they do. . .

David Crespi: Its almost a marketing strategy that works, you know? Its not my fault. I have a disease.

Tilda: Withindays of ingesting Prozac, David Crespi became troubled.

Jessica Crespi: Towards the end of just talkingback and forth and he said, Do you everfeel like life is too dark to go on?

David Crespi: Its crazy. Its not the way i think. Those thoughts arent natural to me.

Kim Crespi: I recall a few events from theday before that would suggest that he was going psychotic. David was jumpingout of the bed and walking around a throw rug and hitting each corner and thenjumping back into bed. And Im going what are you doing? He goes, it just feels good. Well, now i attribute that toakathisia.

intercutpolice band radio crosstalk

Kim Crespi: Our tragedy was January 20, 2006.On that day, I took all the kids to school, left to go get my haircut, left thegirls in the LOVING CARE of their father; they wanted to spend time with him.When I came back into the neighborhood after being gone for an hour-fifteenminutes, I saw a police barricade, and I saw some of my very concernedneighbors coming towards me.

INSERT POLICE CAR WITH FLASHING LIGHTS - OR, TAKE THE SAME CLIP OF THEIRHOUSE - AND RUN IT IN REVERSE!

The policeofficer asked my name and i said my nameand he said were going to need you in this house

sfx: sound ofphone dialing: and then 911, wheres your emergency?

(911-Call)

911 Dispatch: Police Department

David Crespi: Yes. i just killed my twodaughters.

911 Dispatch: You just what?

David Crespi: i just killed my two daughters.

Kim Crespi: I called my Dad in California andI made sure my stepmom was there, and i said, Dad, I have to tell you somethingreally hard. Im in the back of a police car and ive been told that David killed Samand Tess.

David Crespi911 call:

911 Operator: What did you do to them?

David Crespi: I stabbed them

911 Operator: You stabbed them?

David Crespi: Yeah.

911 Operator: How many times did you stab them

David Crespi: I dont know.

911: Keeptalking to me, because you sound a little bit tired

David Crespi: This is for real

911 Operator: Oh, I know its for real, Sir. Everybody is on their way, okay?

INSERT SUICIDE1BY VICKI

Kim Crespi: And Cathy, my stepmom adored Samand Tessas we all didand she started wailing. And I could hear her on thespeakerphone and my Dad goes, Honey, Dave would not do that. David is not like that. Youre mistaken. And I said, I wish I were, but Im in the back of a squad car

SFX of siren sounding. view from the back seat of thepolice car looking forward as the siren wails.

Tilda: TheCrespi children were escorted from school by the Police and were told nothinguntil Kim arrived at the station.

Kim Crespi: They really thought that their dadhad killed himself.

LEAVE TINY AUDIO SPACE-TOO TIGHT

JessicaCrespi: (teary-eyed) My Mom came in and told us, theyre telling me that Dad killed yoursisters. We had to use the language theyre telling me because we couldnt believe that is what actually happened.

Kim Crespi: The idea of him killing Tess andSam was so foreign, but they knew something had happened. And thats how the whole thing started. . .

David Crespi: I went to the doctor and i canremember saying Im afraid I may hurt someone. And she said, Youre too compassionate to do that.Thats just the depression talking. NEVER was anybody saying, the medicine can do this.

Kim Crespi: Psychosisthe drugkilled ourdaughters.

David Crespi:Who I am waschemically altered.

JessicaCrespi: My Dad in hisright mind wouldn't have done anything like this.

David Crespi: I can remember this battle of these thoughts arent real.

Kim Crespi: Because when you have a completepsychotic break like that, and you kill two of your most treasured people inyour lifepeople that every other dayevery other day he would have died for them.

David Crespi: What I did was done on a co*cktailof legal drugs.

Kim Crespi: We were doing what the doctorstold us to do. We were being responsible.

David Crespi: Just because somethings legal doesnt mean its safe.

Kim Crespi: I suspect anybody hearing mystory will go, yeah, thats not going to happen to me, but it could. If it happened tous, it could happen to anyone. .

Begin Kaval Siriagain -

David Crespi: But I know for certain, I knowwhat caused the death of my daughters. I know it was the pills.

Kim Crespi: And for all of that, were serving two consecutive life sentences.

music; celldoor sfx; - return to b-roll silhouette of bmx biker in the glare of the sun.screams of laughter as we see the slo-mo shot of the silhouette then turn toblack

DavidCarmichael: On July 31st,2004, I had been on Paxil for three weeks. . .and I took Ian to a hotel room inLondon, Ontario.

B-roll-out-of-focus hotel barely evident

David: At 3:00 in the morning, thinkingthat he had permanent brain damage, that he was in living hell, he was going tokill my daughter, Gillian, and he was going to harm other kids, and my wife wasgoing to have a nervous breakdownwhich were myfive delusionsI strangled him, and I sat with hisbody for six hours until I called the police at 9:00 in the morning, verycalmly saying that Id committed homicide and opened thedoor for them, and then I was arrested and charged with first degree murder.When the police came in and arrested me, they asked me why didnt I run. I said,I wanted to stay with my son. Hes in a better place now. He was inliving hell. And I stayed with him as long aspossible.

Tilda: For 14long days, David Carmichael was psychotic - and suffered drug withdrawals inhis jail cell .. before awakening to the ultimate terror.

DavidCarmichael: The psychosislasted for two weeks and after I came out of my psychosis a couple of weeksafter everything happened, I was devastated. I cried for three days insegregation at the London Middlesex Detention Centre. I could not believe whatI had done.

Tilda: Ianwas laid to rest by Davids family. Itwould be months before DNA tests indicated that Carmichaels body was unable to metabolize the Paxil hed ingested and that the drug was the likelycause of this unthinkable act. Dr. Peter Breggin says hes seen it all before.

Peter Breggin, MD (Psychiatrist and Author): Many people do not have the arrayof enzymes in their livers to properly destroy SSRI drugs when they get in thebloodstream. So the drugs pass through the liver, and they dont get metabolized, meaning they dont get broken down. You might get the equivalent of a10 mg dose of an SSRI, but in your blood it is 30 or 40 mg. And there arestudies correlating the violence with the lack of the enzyme for these drugs.

DavidCarmichael: The publichas no understanding of how Paxil or other SSRI could trigger a homicidalpsychotic episodeand they may not care, but there isevidence based on DNA that Paxil did cause me to kill my son, Ian. Its something that I have to live with. Even when Im out in the public, my stigma is off the chartcompared to the stigma around mental illnesses. But if people beat me upemotionally when Im out there, thats fine. Theyll never beat me up as much as I beat myself up for along time.

VO: For her part, Gillianwho was only 14 when the tragedy occurredsays she grew up the day she grasped what had really happened to her father.

GillianCarmichael: I realizedwho he was before, who he was during the period of time that he was taking themedication, and I realized that they were two different people.

Tilda: Davidcredits Gillian as the reason he did not take his own life while in prison.

David: There were several times when I waseither in jail or in a psychiatric hospital where I felt like taking my ownlife. What kept me going was my daughter, Gillian. I had one line and it was, Im a good dad. Im going to be a dad again. And that was my hope. And I knowGillian, whatever she was doing, wherever she was, was thinking that she wantedher dad back in her life too.

Gillian: How can I not accept him back? Hes an amazing man. Hes my father and I love him.

Tilda: David Carmichael was found not criminally responsible for his sons death as two psychiatristsone working for the defense and one for theprosecution, both agreed that he was psychotic at the time of the tragedy.

David: The public is not going to careabout this (motioning tohimself crying). Theres no empathy for me, but I think, Ill tell you what the pain will never go away.

Gillian: Ian was just an amazing person andhe was an amazing brother. And he was an amazing friend and amazing son. Hejust had so much life. [tears up] yeah.. sorry

Kevin P. Miller: Pretend that Im the Glaxo CEO. What would youlike to say to me?

DavidCarmichael: [Long pause- 22 seconds]

David: If youre the GlaxoSmithKline CEO, I would like to encourageyou to be more honest with the Canadian public. And if there are serious sideeffects to any one of your drugs, its not just about sending out notices to health careprofessionals that many have never read. Youve got to go directly to consumers and make them awareof some of these dangers. Thats aresponsibility that you have as a drug company.

fade to black

under blackconfusing mix of voices under black.Thenvery, very slowly BEGIN revealingvideolittle-by-littleas if it were like a video of thesun rising. begin cacophony of 1991 Prozac hearing testimonials under black

Pallie Carnes: I was only put on it for weight loss. WEIGHT LOSS!

Susan Williams: My sister did commit suicide infront of Lindsay

Debra Douglas: That gun, I later learned, wasloaded with hollow-point bullets and I shudder to think what could havehappened

Mike Donnelly: The only way to have peace andserenity again was to die

Robin Schott: Do all of you want to take thisdrug? Do all of you want to walk around humiliated for the rest of your life

Tilda:Thirteen years had passed since the dramatic 1991 FDA-Prozac hearings. By 2004,The British government had virtually banned SSRIs for children and youngadults, in light of the real risk of suicide and violence. But in America, theU.S. FDA remained unconvincedand demandedmore studies. This was welcome news at Pfizer, GSK, and The House That Prozac Built.

Dr. Bob Temple, Food and Drug Administration: We didnt know what the results would be. We had no idea, butwe thought getting as right an answer as possible was the right thing to do.

David Healy, MD: In 1983, nine years before thelaunch of Zoloft in the United States, 21 years before the FDA required Pfizerto put a black box warning on it, Pfizer had done a healthy volunteer trial onZoloft in Leeds in the UK. They recruited 12 women to this trial. Half of themwere to be given Zoloft, the other half were given a placebo. The trial was dueto run for two weeks but stopped after a week because every single woman takingZoloft had become anxious, apprehensive, agitated. One or two had begun tovoice thoughts about harming others all of the things that led FDA toput a black box warning on this drug 21 years laterwere there in 83. What was more, Pfizer looked at this trial andwrote down, Zoloft has caused this problem.

Tilda: ForMathy Downingand thousands like herthe earth-shattering epiphanies came weeks too late.

Mathy: Ironically, it happens that thedoctor that approved Zoloft as an antidepressant for childrenTom Laughrenironically, I know this man. Ive known him for quite a while because both of hisdaughters attended school with my daughters for eight years. . .

Tilda: Forover 20 years, Thomas Laughren was head of FDAs psychopharmacologydivision.

Mathy: I had no idea he worked at FDAuntil I saw him on the FDA panel three weeks after Candace died. I sat therewith my husband and we listened for eight hours while person after personbasically told our story. I went up to speak with him when the meeting was overand I said, Where can I find information aboutthose contraindications? And he told me he would give me a list of people forme to talk toand then I never spoke to himagain. I mean, hes a father of two of my daughters friends. I really did think hewould follow through and help me gain the information I needed, but he didnt.

Tilda: Asfate would have it, yet another FDA hearing on SSRIs and violence was held inSeptember 2004. In one brief, emotionally-charged moment, Mathy Downing steppedup the microphone.

Mathy: And when I spoke at the FDAhearings on September 13, I addressed him personally.

Tilda: Aftermonths of grievingand too-few answers, Mathy Downingfinally let loose.

Mathy: The blood of these children areon your hands. (gasps fromcrowd)

Peter Breggin, MD - I remember seeing Mathy Downingstand up at the hearing andconfront Laughren and the other FDA panel members and say the blood of my daughter is on your hands. And she was right.

Tilda: Later,Mathy Downing learned that Thomas Laughren had been in the thick of the SSRIcontroversy since well before the 1991 Prozac hearings.

KAREN BARTHMENZIES (Attorney andPatient Advocate): Some of the senior officials at FDA, some of the people we find as theoriginal culpritsthe problem at FDA, are Dr. BobTemple; Thomas Laughren is horribly guilty. All these same individuals wereinvolved back in the early 90s when this risk was being raised and identified,and rather than pursuing safety concerns or requiring drug companies to do moreto determine if this is a serious risk, they looked the other way.

Tilda:Laughren left FDA in 2012 and started a new business, dedicated to helping drugcompanies get FDA approval for their drugs. But he was not alone at theintersection of public service and personal profit.

DANIEL CASEY,MD (from 1991 Prozac Hearings): I do not find from the evidencetoday that there is credible evidence to support a conclusion thatantidepressant medications cause the emergence or intensification ofsuicidality and/or other violent behaviors

Tilda: WhenDr. Daniel Casey resurfacednine yearsafter the 1991 Prozac hearings he chairedhe did so as a paid expert witness for Pfizer.Attorney Andy Vickery conducted the deposition.

Vickery deposition: You were the Chairman of that committee for severalyears, right?

Dr. Casey: Yes.

Vickeryinterview: Thechairman of that committee who is moderating it in a public building in apublic place was wearing a bullet proof vest

Vickery deposition: Dr. Casey, did you wear a bulletproof vest to thatforum?

Dr. Casey deposition: (startled) Yes.

Vickery deposition: Had you ever worn one prior?

Dr. Casey: No.

Vickery deposition: Have you ever worn one since?

Dr. Casey deposition: No

Vickeryinterview: .because he thought one of the family members of thepeople being harmed by Prozac would shoot him.

Vickerydeposition: Youcertainly did not believe it was the folks on the Eli Lilly side of the coin,did you?

Dr. Casey deposition: (smirks, then quickly changesexpression) No

Vickery interview:No conflictof interest?

Vickery deposition: and yet that would not effect your objectivity. Isthat your testimony?

Casey: Yes.

Tilda: Others, like Harvard Universitys influential Dr. Joseph Biederman (Bead-err-Min) also seem to display an unnervingindifference to their conflicts-of-interest. Here, Biederman was being deposedas a key thought-leader one of those most responsible forspreading the off-label use of the antipsychotic Risperdal to millions ofteens.

Attorney deposition: Professor, what rank are you?

Biederman: Full Professor

Attorney deposition: Whats after that?

Biederman: God.

Attorney: Did you sayGod?

Biederman: Yeah.

SLATE:

Text: Dr. Biederman earned more than $1.6million from drug makers for promoting antipsychotics as a mainline treatmentfor pediatric bipolar disorder.Even afterwithholdingthe depth of his financialconflicts-of-interestfromCongressional investigators,Biederman wasnever penalized for his ethicsviolations.

fade toblack. LEAVE 2-3SECONDS

- Then titleappears:

Netherworld

KristinaGehrki: She hadbeautiful blue eyes. . .she was very smart, artistic-incredibly artistic. ..was very inquisitive. . .she seemed to root for the underdog, and would try tohelp people who were maybe less fortunate .. that quality of caringabout others and caring about the world at large. It was with her until thenight before she died.

Tilda: Theres no doubt that Natalie Gehrki was a creative spirit an artist. Her mind wandered withthoughts of Bukowski and Oscar Wilde .. often with inspired optimism and an endearingchildlike innocence. But there was also confusion .. and yes, darkness. ..visits to a netherworld Natalie couldnt understand.

DrowningScene: Natalie is hit with water in theface as the vision shifts to drowningwith water violently whippingaround her.

ACTRESS as Natalie: The memories of everything Ive ever done wrong since thebeginning of my own moral recognition come flooding in all at once like hightide .. and the cold water wakes me from a dream. I suddenly realize Ive forgotten how to swim, but thewaves pay no mind and pull at my useless body. Reality burns just as bad assaltwater. First its in my eyes, then its in my mouth, trickling down into my lungs, fillingme to capacity. Painful memories anchor me. . .and the sea is getting rougherand there is no more shore. Waves whip from every direction, and the ocean ismerciless and I cannot breathe.

LEAVE PREGNANT PAUSE

I am drowning.. please help.

(natalie descends underwater, arms aloft as bubbles rise towards camera)

How did I forget how to swim?

LEAVE PREGNANT PAUSE

How do I remember?

Lennon song, How?(by Anja):

How can I go forward when I dont know which way Im facing?

How can I go forward when I dont know which way to turn?

How can I go forward into somethingIm not sure of?

Oh no, oh no

Tilda: Bornwith juvenile rheumatoid arthritis, Natalie was prescribed a strong drug calledMethotrexate - a cancer drug - to combat it. On doctors advice, she began using antidepressants in the 5thgrade. The year was 2005, and Natalie was only 11the same age as Candace Downing when she was diagnosedwith text anxiety and prescribed Zoloft.

Kristina: One day, I walked into Natalies room. . . she wasnt showing any emotion and she was very monotone withme. And she said,

ACTRESS asNatalie: Mom, Sometimes I think about killingmyself, but I know I cant, so I wont.

Kristina: And I said, oh my God, Natalie, why?

ACTRESS as Natalie: In my mind, it made complete sense at the time.

Tilda:Kristina rushed Natalie to the hospital. When she was admitted, no one therementioned that the side effects likely stemmed from the Prozac she was given.Instead, they supplemented the Prozac with Benadryl and the antipsychotic,Risperdal.

ACTRESS as Natalie: (Harleigh05 @ 1:26): I cried uncontrollably as a malestaff member put a hospital wristband over my wrist. He prescribed meRisperdal, a powerful anti-psychotic, which of course, I knew nothing about.But I had to do what he told me to, so I took it.

Kristina: In the hospital, she was asked towrite down her feelings: I wish I could stop thinking about wanting to killmyself. . . I hate my mom, I hate my dad, I hate my brother, I hate my house, Ihate my life. And I dont know why.

(Harleigh06 @ 47 sec -which is take 3): I dont trust modern medicine orpsychiatrists at all. My textbook psychiatrist continued to tell me everytime I cried and begged to be released: If you really want to go, you haveto listen and follow everything I say.

Tilda:Throughout Natalies teen years, her online diarycomplained of a lack of sleep, in between ruminations on the human existence .. . her existence.

(Harleigh13 @2:24) My secrets build up inside of me like the tsunami wavemy brother and I saw on TV once. The secrets are ready to crash over, ready todestroy. I will not let them.

Kristina: When you give a person a drug, andyou dont tell them about any of the sideeffects, and they get side fx. . .they are going to attribute them tothemselves or their underlying condition.

(Harleigh13 @59 sec): every day im breathing is a small miracle

Kristina: She attributed all her side effectsto herself.

(Harleigh14 @2:11 sec): I wish I could figure out how Ifeel about who I really am.

Tilda: In2012, Natalie was switched to Zoloftand by November, her doctor increased the dose from100mg to 150mg unbeknownst to the Gehrkis.

(Harleigh14) at59seconds: Picturing myself in the future is an impossible conceptfor my mind to comprehend. Its like trying to explain colors to someone born blind. Ijust cant do it.

Tilda: In Februaryof 2013, without seeing her patient, the doctor increased Natalies doseover thephonefrom 150mg to 200mgthe maximum dose legally allowed. Four days later, onthe afternoon of February 6th, Natalie was struggling:

(Harleigh08)at 1:40 seconds: I keep coughing up blood. Im not hungry. Its time for me to take my meds.

Tilda: and the world was closing in.

Kristina: in my daughters last months, weeks, days, hours, she had a chemicalimbalance in her brainand it wasprescribed for her

(Harleigh07)at 2:15 seconds: I was different before, and now I have changed -chemically, maybe: neurologically, who knows?

Kristina: . . .she did not have a chemicalimbalance before she took the prescription. . .but she certainly had a chemicalimbalance when she died. . .

(Harleigh09)at 1:51 seconds: The silence grows around me in petals, warm andburgundy, wrapping a thorny fence. . .Do I cry, scream out, beg?

Lennon song: How can we go forward intosomething were not sure of?

Kristina: This is a poisoning, this is not a traditional suicide and we oughtnot call it such, because by using that very word we create a false reality. becauseit is not only disrespectful to the victim and their families, but to call itthat also plays into the hands of the pharmaceutical companies and the doctors.Because byusing that very word, we create a false reality.

(Harleigh11)at 10 seconds: Im very sorry. I have failed. But its okay, Ill be much happier this way. Burymy body under a tree, somewhere deep in the woods. Take care of Gypsy for me.Move onIm not worth mourning.

Kristina: I fear for other Natalies out there, and I almost beg people, Dont be me. Dont be our family. Because (chokes up) Our daughter is gone. And shewanted life. She deserved to live. And shes not here anymore.

close outwith music. . .

fade to black

CG (on black)appears:

One joy scatters a hundred griefs.

-Chinese saying

Tilda: IN AREMOTE TOWN IN WESTERN CANADA, the Stephan (Steff-enn) family was facing a life and deathstruggle in the shadow of the Rocky Mountains. Two of Debbie Stephans children were exhibiting the same symptoms that hadultimately claimed her life: Joseph was becoming frighteningly violent and his sister Autumn wassuccumbing to severe bipolar, with its mercurial mood swings. Their father,Tony Stephan, was desperate and searching for any way to save his children, whendrug after drug failed. The answer came from what seemed the unlikeliest ofplaces: micronutrients - mainly minerals.

JosephStephan: I rememberthe earlier days of doing the testing with nutrients and different things. Ithink they were trying to reduce some liquid mineral thing so you didnt have to drink a whole cup; maybe just an ounce. AndI dont think it worked very good, and itsmelled funny. I remember the smell and can still taste it in the back of mythroat. (smirks) I think they burned itIm notsure.

Tony Stephan: At first it didnt work. It did not work.

JosephStephan: I justremember I was out camping and I had a little bottle ofI call it rust water it was the color of rust, and I wassupposed to drink a little ounce of that every day, a couple of times. And so Iwould be doing that. I mean, it was so experimental that I didnt really understand what we were doing.

Tony Stephan: We put him on a co*cktail thatcontained vitamins, minerals, antioxidants and amino acids.

AutumnStringham: I wasabsolutely livid when i found out that he had taken Joseph off of his medication, and I said some terriblethings to him. I told him it was on his headthe next suicide in this family was going to be hisfault.

Tony Stephan: I remember about six weeks intothis program that we sat together on the couch and he said where was I? what happened to me?why was i so angry all of the time? I said, Dont go there, you dont have to. Live the day now. Youre here. Be in the present.

Joseph: It was like one day wakingup and like a fog had completely lifted, and that was amazing. It was a veryreal turning point in my life.

Tilda: WithJoseph on the mend, Tony Stephan then turned his attention to his daughterAutumn, who had been in and out of psych wards.

AutumnStringham: I ended upin my dads custody and he has a friend whowas a male psych nurse who decided to hang around the house a lot and honestly,I look back on it now, I think that they were waiting for a moment when theywould have legal justification to force me to go on this micronutrient stuff.At that time, it was this crazy concoction with liquids and powders, and pillsand things and I had said no, and my husband had said, No. Were not doing that. My psychiatrist said, No. In fact, he said, Dont rock the boat. You will die. Donot go off of this medication. And I was on that five-drugco*cktail at that time. So, I had absolutely no intention of doing what my dadhad already started with my brother Josephno intention.

Tony Stephan: I wont say that I forced her to do it because thatdoesnt sound politically correct (smirks), but I constrained her todo it. And she just didnt believethat this was going to work at all. And I said, Just keep taking your medications.I dont care. You know how to take your meds.Take this with it. Just keep taking it.

AutumnStringham: So theywaited until I had a little med breakthrough and I went rummaging for a knife,and there was some screaming involved, and he and this friend of his whohappened to be a psychiatric nurse, stuffed me with a bunch of Ativan and putme to bed. And then, while I was still really nicely sedated, began forcefeeding me the concoctions.

BonnieKaplan, Ph.D (Professor,Faculty of Medicine, University of Calgary): Back in 1996, when I first metAutumn Stringam, it was the first day I also met her father Tony Stephan. Shewas sitting there in front of us, completely normal, very bright, veryarticulate, very charming young woman, doing very well on vitamins andminerals, but she had lived through this horrible, horrible period and couldremember it so vividly. It was very impressive. You knew that you were hearinga true story, and I think that that has come through consistently with Autumn.

AutumnStringham: I recognizethat a huge percentage of people with bipolar commit suicide and it just aseasily could have been me, and isnt, because something really beautiful happened in mylife. And I have to acknowledge that thats not just mine to take and run away with, but thattheres a lot of good that can be done inthe world, knowing what I know now.

Dr. BonnieKaplan: These werejust three people from Southern Alberta, who believed that they had fixed two children in Tonys family and they did it with vitamins and mineralsoff the shelf. And they just desperately wanted a scientist somewhere to takethem seriously and do some research.

Tilda: WhenStephan and Truehope approached Dr. Kaplan in 1996, she was the Director ofBehavioural Research for the University of Calgary. As a scientist, she washighly skepticaland thought the notion of utilisingminerals for mental illness was simply preposterous.

Tony Stephan: I think Bonnie, when we first mether, she kind of thought that we were flaky because all of a sudden, you havethese two strange dudes coming from Southern Alberta and theyve got this idea that you can take people sufferingwith these intractable, incurable mental disorders and change them and bringthem around, when all along, science hasnt been able to do that.

Dr. Kaplan: And I thought, Well, thats impossible. You cant do that. Theres no way it would have that effect. But I think that line of thought isreflective of our lack of education about nutrition, and the fact that blood isbathing the neurons in our brain every minute of every day, bringing oxygen andwhat? Micronutrients to make those brain cellswork.

Tilda:Stephan and his co-founder created a non-profit called Truehopeand after years of experimentation, they developed amineral-based formula called Empower Plus. Intrigued by Autumn and Josephs successful transformations, Dr. Kaplan and otherscontinued studying the formula for bipolar disorder, ADHD, and depression.

Kaplan (TV clip: 2001): Some people call this a micronutrient sledgehammer,because its all of the vitamins, and a verylong list of dietary minerals. The patients in this sample got much better, infact more than 50% better. Quite a few of them were more than 75% better.

AutumnStringham: He wasnt trying to build an empire when he set out to save meand Joe. It was not a deliberate act. Hes not a formulator. It was a conversation that led toan idea that led to an answer and thats all he was ever in it for. And hes faced so much opposition for doing the right thing.Hes faced a lot of opposition forthat and I think its changed the course of his wholelife.

Tilda: As ithas with Dr. Kaplan. When she first presented her findings about the Truehopemineral-vitamin-combination to the Canadian Psychiatric Associations Annual Meeting in 2001, she and the company were immediately under attack.

Dr. Kaplan: When I went to graduate school,they did not prepare me to be personally attacked for just doing objectiveresearch. That was a little shocking. We took a lot of arrows for about fiveyears especially, longer for the Truehope people, but it was very, very tough.

Tony: When you try and investigate anew paradigm, the resistance is incredible. I watched Dr. Kaplan go throughthis. We had major resistance form Health Canada shutting down trials. Here,the Alberta government had provided $554,000 so that she could continue thework. Health Canada came in and swathed the trial. They destroyed it.

COMMON SENSEmusic bed

Tilda: HealthCanada not only shut down Dr. Kaplans scientific investigation into micronutrients andmental health,

START WIDE ON STUDYZOOM INTO THIS STUDY HAS BEEN TERMINATED

they orderedTruehope to stop manufacturing Empower Plus. When the company refused, theyseized the product at the US-Canadian border and banned it for sale in Canada.

Tony: Why? Were talking about vitamins and minerals here.

RobertWhitaker (PulitzerPrize finalist): Well, what that tells you is that anything that cha llenges commercialinterests, such as micronutrients might be a good thing to do, boy, there arepowerful forces behind a commercial storyand they will come forth.

Tilda: WhenTruehope fought back through the Courtsand wonit wasnt long thereafter that Health Canada mobilized theRoyal Canadian Mounted Police to conduct a guns-drawn raid at the Truehopeoffices in Alberta.

Ian Stewart: Health Canada spent $2 million toprosecute Truehope for chargeshad they beenfound guiltywould have amounted to a $375 fine.They lost Health Canadalost, but all of those costs to defend ourselves were not recouped from HealthCanada.

Tilda:Despite Pharmas falsified scienceand billion-dollar fines for fraudulent marketing

BLACK HEALTHCANADA LOGO W/ PINK FLAG

and in spite of millions who were harmed bypsychiatric drugsHealth Canada decided that it was this tiny non-profit that needed to be shown the fullmight of the Canadian government.

BonnieKaplan: There hasbeen a huge bias against nutrition research. Whos triggering that? Who what is the political agenda thatis continually bombarding us with the message that taking vitamins and mineralsmight not be a good thing? I dont get that.The result is that there is a lot of bias against people whos saying Not only should we take them, we should be studying itmore and we should see whether or not theres treatment benefit from vitaminsand minerals.

Julia Rucklidge (TedX talk at 55sec): What Im going to talk about today may sound as radical as handwashing sounded to a mid-19th century doctorand yet it is equally as scientific.It is the simple idea that optimizing nutrition is a safe and viable way toavoid, treat or lessen mental illness.

Tilda: Afternearly two decades of wrangling with Health Canadaand three-quarters of a million dollars in court costsand legal fees for Truehope, researchers Bonnie Kaplan, Julia Rucklidge, andothers continue to investigate the use of nutrients as a primary treatment formental health. Yet the road has been anything but easy.

Rucklidge: I was very aware of how manypeople were incredibly skeptical about this work. I was trained as a scientistand we need to evaluate the evidence. What has astounded me is the obstaclesthat we faced in order to try to answer what, I think, a very importantquestion for our community.

Bonnie Kaplan: I think there are two thingsabout the Truehope formula that are really special. One is that its broad spectrumnot just vitamins but both vitamins and dietaryminerals.

Anotheraspect of looking at the weight of the science is to look at replication,replication not within the same laboratory, not in the same hands but whenother people say

CHANGE BACK TO CAM1

Aha, Im getting the same result. So, its very important that the use of broad-spectrumformulas is being replicated in multiple countries, in New Zealand, in theUnited States, in Canada, with different formulations, in the UK, in Holland,in Australia, that is extremely important.

Fristad: What people get concerned about isif a company is trying to simply market their ware without enough sciencebehind it; people become very skeptical, very quickly.

So what Iwould say in favor of Truehope, is that none of us who are investigating theproduct have any financial ties to the company whatsoever,

FRISTAD STUDY

and then theyhave absolutely no ties whatsoever in how we publish our findings. So they haveno authority over what we write, where we publish it, where we submit it, etc.

Rucklidge: There have been times where Ive been at absolute despair and say, Why am I doing this? Because I have gone through somany obstacles to be able to run the studies that I do. Some of the obstacles Ive come across have shocked me. Its not fair for me to say them on camera of what kindsof things that Ive had to deal with from members ofmy community.

KPM: Have you been betrayed?

Julia R: Yesuh-huhyep.

KPM: Is this, dare I say, dangerous work for you to embark on?

Mary Fristad: Well, I wouldnt have started my career this way. That might haveended my career.

Kaplan: Would I do it again? I dont know if I would have the energy to deal with HealthCanada again.

Mary Fristad: It is understandable that peoplewould have questions, I would simply ask that people then be open-minded to theresults as the science evolves.

Tilda: In reality, though, Truehopeand nutrition research in generalis in danger of becoming extinct. Despite being themost studied dietary supplement in the world, good scientists often fear thepolitical consequences of studying nutritions effects on the brain.

Rucklidge: It makes perfect logic to me thatwe should investigate other options. If someone comes along and has some intriguingdata that shows that symptoms can be controlled by another method that may notcome along with so many risks, then I think its in our place as scientists to study it.

Kaplan: I happen to think that medicationsare very important especially inacute crises. But, to me theyre thesupplement. I believe that it would be more beneficial to a lot of peopleespecially developing children, to be treated first with everythingpsychosocial, family therapy, etcetera, and nutritional, which is not going tocause any long term harm, and that that should be primary intervention.

Tilda: For people who have become wellutilising vitamins and mineralsaftersuffering from the fog of pharmaceuticalsthey cannot conceive ever going back.

Nicole: I found out about Truehope afterhaving my last child. It was the darkest hours of my life, days, months and itended up being two years. I have a huge amount of gratitude that I need to sendto Truehope, the whole, entire program of it. It kind of makes me emotional.They changed my life. For so many other people, theyre changing lives every day. If we, as parents, asmothers, as fathers, as brothers, as sisters, can just take a look at that

Sonya: In the fall of 1996, we contactedDr. Kolb and he told us about Tony Stephan and Truehope. We had been lookingfor some alternatives. Wed giveneverything the psychiatrist had suggested, we gave it all a try. Nothing wasworking. We felt there must be something else. I think heres a product that worked for me. It helped me. Thereare no side effects. Im afunctioning part of society. Im not on thefloor in a ball crying all the time. I mean, that was my life before. I cancontribute to the wellbeing of my own family and my community and, hopefully,society. And Truehope has helped. Maybe, its not for everybody but the option needs to be there.

Jeri: You know, they always talk aboutthe placebo effect. I dont think aplacebo effect last 11 years, but if it does, bring it on. Ill keep it. (laughs)

Autumn: I don't want to begiving people false hope that everything about their mental illness is going toturn around, flip a switch, and tada a magic pill. Thats not the case, but my goodness, just stopping the hallucinations, justthat wouldve been enough to keep me on it therest of my life because that was huge. It took me two more months to get offthe rest of my medication and Id say the betterpart of the year before I felt like I was just really stable.

There are going to be people who want to say that Im just trying to make a lot of money off of a big made-upstory, but my mothers dead in the ground. Her dads dead. We all know how that happened. She had aprescription, and theres some things you just cant argue with. Im not dead. Ive got four healthy kids and a greatmarriage. And thats something I didnt expect would ever happen with me.

EPILOGUE

TILDA: Thelesson of a generation's worth of psychiatric experiments is that regulatorsdidn't protect the public; doctors didn't protect their patients; journalistsrefused to ask the tough questions; the pharmaceutical companies played thesystem and profited handsomely; and millions suffered, died, became addicts, orwere otherwise harmed.

END w EARLIER MELISSA B-ROLL WALKING BY THE CAMERA IN SLO-MO;

Melissa: You know, alot of times parents think that their eight- or nine-year-old just won'tunderstand; it's just easier to just give them the medications. But not tellingyour kid why they're taking the medication or what the medication is supposedto do can be really harmful. Having that kernel of knowledge that these thingsthat I was experiencing weren't me but were caused by a medication, I thinkwould've saved a lot of pain. A lot of pain.

Bob B: Weve been thru alot. And she stopped taking the drugs and a new kid came forward. Straight As at the Univ.of St. Thomas; summa cum laude; valedictorian; Unbelievable. Here is this childthat i was afraid would never get out of her bedroom is now doing what shes doing. (chokesup) So, its a great thingthat i have a kid who has the tenacity and the ability to tell us what sheneeded. And Im afraid thereare a lot of kids who arent like that, and theyre going to bein a stuporor worse.

Tilda: Theseare stories of those who have fallen

and of thosewho have somehow survived. Many lost sons and daughters .. brothers and sisters and their tragedies forced these private people out ofthe shadows. They wanted answersand were notinterested in the politics of medicine. If the truth had been afforded usdecades ago, millions would have been spared similar fates.

LindaHurcombe: These arevery primitive things, missing your children.You miss their warmth and their smell and their lovely, lovely presence.

VOX: Perhaps change is coming, albeittoo slowly. But until it occurs, we should take nothing for granted: not ourloves .. nor our lives .. or the gift of our families and friends. As these Letters From Generation Rx have taught us .. there is perilin the conventional wisdom of treating so many people .. so indiscriminately ..with such powerful, life-changing drugs.

ShaunMcCartney: If somebodysaid to me that Brennan could come back to life and Id never see him again, but I know that he could livehis life, the biggest loss for me, is the wonderful life he could have had. Hewould have been a great dad. He was a great friend to everybody. If thats what it took, then I would do that in a second.

Tilda: Asthey mourn Every birthday, every holiday; every anniversary of a loved one'sdeath, their only prayer is to stop this from happening .. to anyone else.

-fin-

EPILOGUE-Slates

After15 years of political infighting, MP Terence Youngs legislation, BillC-17 passed unanimously in November 2014. Named Vanessas Law after Mr. Youngs daughter, the lawgives the Health Minister the power to recall unsafe drugs, requiresmandatory adverse reaction reporting throughout Canada, and provides an onlinepublic registry with all clinical trial data about pharmaceutical drugs. BillC-17 also demands greater transparency from Health Canada Canadas version of the FDA.

RobertWhitakers book, Anatomy of an Epidemic appeared on the NewYork Times bestsellers list for the first time in April of2015. Whitaker was honored by the Investigative Reporters and EditorsAssociation with their 2010 Book Award for Best Investigative Journalism forAnatomy of an Epidemic.

AutumnStephan Stringhamsstory about her familys battle with mental illness, APromise of Hope was published by Harper-Collins Canada. Within months, itbecame a Canadian bestseller.

DavidCrespi is still in prison for the drug-induced deaths of his daughters. Hiswife Kim is committed to freeing him.

Letters From Generation RX | Journeyman Pictures (2024)

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